May 1, 2024

Histomorphometry Studies

Medical Histology is the microscopic study of tissues and organs through sectioning, staining, and examining those sections under a microscope. Often called microscopic anatomy and histochemistry, histology allows for the visualization of tissue structure and characteristic changes the tissue may have undergone. Our scientists are highly trained in histomorphometric techniques on validated systems to enable routine or specialty analysis designed to accurately measure product performance.

Some typical measurements include:

  • Percent bone ingrowth as a function of an area (a defined region of interest; ROI)
  • Percent residual implant material as a function of a defined ROI (e.g., defect or fusion mass)
  • Percent of a target tissue type (e.g., fibrosis) as a function of a defined ROI
  • Percent of a target tissue type as a function of tissue or implant length (e.g., percent osteoid on a bone ingrowth surface)

VetPath Consultants offers validated state of the art histomorphometry studies. There are many applications for these determinations.  We support a wide range of therapeutic areas for histomorphometry and image analysis including orthopedics, ocular, cardiovascular, ablation, wound healing devices.

Our additional specialized studies include:

NEOINTIMAL HYPERPLASIA

OSTEOPOROSIS

AORTIC PLAQUE FORMATION

RETINAL PROLIFERATION

SUBRETINAL PLAQUE FORMATION

BRONCHIAL HYPERPLASIA

DEVICE IMPLANTATION 

 

Our scientists are highly trained in histomorphometric techniques on validated systems to enable routine or specialty analysis designed to accurately measure product performance.

We are fully GLP compliant, with multiple consulting Quality Assurance professionals to audit critical processes.

At Vetpath, we also work with additional histomorphometric specialist in our histology studies.

 

Further Histology Services are provided by Scientific Solutions, LLC.